BDBM228816 5-Cl-PZA

SMILES NC(=O)c1cnc(Cl)cn1

InChI Key InChIKey=GFEFMHWOSWUJSO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 228816   

TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University At Albany

LigandPNGBDBM228816(5-Cl-PZA)
Affinity DataIC50:  3.32E+4nMAssay Description:Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University At Albany

LigandPNGBDBM228816(5-Cl-PZA)
Affinity DataIC50:  3.32E+4nMAssay Description:Antagonist activity at oxytocin receptor in rat uterine strips assessed as inhibition of oxytocin-induced contractionMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University At Albany

LigandPNGBDBM228816(5-Cl-PZA)
Affinity DataIC50:  3.32E+4nMAssay Description:Inhibition of human recombinant MGLMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University At Albany

LigandPNGBDBM228816(5-Cl-PZA)
Affinity DataIC50:  3.32E+4nMAssay Description:Inhibition of His-tagged human SIRT6 expressed in Escherichia coli BL21(DE3) using Ac-p53 as substrate by fluorescence-based coupled-enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed